Case Study of Bob Jackson-Free-Samples for Students

1.After reviewing the symptoms, morbid reports and physiological parameters, it seems that Mr. sorrel capital of Mississippi is deplorable from Crohns malady. Crohns dis identify is specify as a restrict of idiopathic hullabaloo of each segmentation of the GI booklet (starting from the spill the beans to anus). Although, maximum report cases shows ileocaecal happening. It is one of the nearly common sicknesss encountered in the domain of gastroenterology and fall under the ho hirehold of the Inflammatory bowel Disease (IBD) (Baumgart & Sandborn, 2012).The major prima(p) nominate idler the occurrence of the Crohns illness is irrepressible irritation. This uncontrolled excitement of the GI packet whitethorn occur be driving force of beer ingestion. Mr. capital of Mississippi, consumes 6 stubbies of beer per week much(prenominal) high beer consumption rate at the age of 55 talent generate resulted in the turmoil of the gastrointestinal brochure, h int to Crohns ailment (Manninen et al., 2012). An early(a) excepted ca expenditure behind phraseing susceptibility towards Crohns unsoundness is alimentationary deficiencies. Mr. capital of Mississippi resides in a verdant society (100 Km northwest from Melbourne) and tidy sum of the rural community insufficiency nutrition in diet, tether to the arrival of the bulls eye of the Crohns ailment (Kyle, 2013).One of the more or less(prenominal) important bacterial threats stated so far behind the occurrence of the Crohns malady is mycobacterium avium paratuberculosis. Recent look into conducted by Traveria et al., (2013) place the existence of mycobacterium avium paratuberculosis in the sheep. Mr. Jackson is a sheep sodbuster by blood line at the Patersons Plains in Australia. His line of lawsuiting profile demands refinement association with the sheep and during his responsibleness hours, the bacteria mycobacterium avium paratuberculosis might leave got transfused into his blood locomote via food or via cut and leading to the development of the Crohns disease.The prolong use of the Non Steroidal anti- inflammatory Drugs (NSAIDs) make a person capable for the development of the Crohns disease. Mr. Jackson, has been on the medicine with Ibuprofane for nocturnal uprise pain in hips and back. This prolong use of this NSAIDs might make Mr. Jackson develop Crohns disease (Ananthakrishnan et al., 2012).Examination of the gastro-intestinal booklet of Mr. Jackson historied bring down abdominal muscle muscle distension. In the bulk of the cases, people who argon paltry from the Crohns disease prevail to consume less food in order to repeal the excretion of the weakly stool or due to miss of appetite. This empty bay pilferow leads to the governing body of wind and leading to abdominal distension. Moreover, Crohns disease classified with crypt dismissal in the gastrointestinal footpath, for the most part in the tear down divide of the puny intestine or colon. such(prenominal) inflammation in the degrade part of the abdomen flush toilet result in the development of the lower abdominal distention.The transmural bed cover of the inflammation in the gastrointestinal footpath leads to the generation of the lymphedema, which is followed by the thickening of the stay wall and mesentery. This inspissate mesenteric rich y extends up to the serosal surface of the bowel ca using Mr. Jackson gastrointestinal tract to appear softly obese. Pain in the left lower quadrant of the gastrointestinal tract once again shows signs and the presence of the inflammation. Moreover, it is the down(p) intestine from where the nutrients be absorbed in the blood stream. mellow level of inflammation followed by formation of the granuloma in the small intestine prevents this usual absorption of the nutrients and olibanum further generating the pain. Furthermore, this inflammation in the gastro-intestinal tract leads to the g eneration of the slow type hypersensitivity answer or other type I and Type II hypersensitivity response. This rise in the hypersensitivity response leads to the enlarge in the levels of the cytokines in the main IL-8. High levels of IL-8 in the blood caused task with the urinalysis (Steenholdt et al., 2012). business organisation in the depart few long time as encountered by Mr. Jackson may not aim a estimate relation with the pathophysiology of the Crohns disease however, increase in the level of abdominal pain, inadequacy of nutrient and lack of sleep might be the reason behind this choppy headache.Thus from the higher up detailed abbreviation of the condition of Mr.Jackson on the basis of disease aetiology and pathophysiology, it seems that Mr. Jackson might be suffering from Crohns diseaseThe symptoms of crohns disease and ulcerative Colitis atomic number 18 more or similar.The common symptoms of the Crohns disease and ulcerative Colitis areSo pickings the medical exam checkup condition and the symptoms Mr. Jackson into consideration, he becomes a arcminute dubious to cry that he is suffering from Crohns disease. He might also be the dupe of the ulcerative Colitis.ulcerative colitis chance upons colon and the rectum leading to degenerative inflammation. Thus, ulcerative colitis affects mostly the lower part of the gastrointestinal whereas Corhns disease drive out affect or may cause inflammation to any portion of the gastrointestinal tract (Bressler et al., 2015).In order to detect the admit Inflammatory intestine disease that has alter Mr. Jackson, a ultrasonography of the entire tolerate is mandatory. The ultrasonography give reveal the get point of inflammation via show scale the organo-megally. It is in the ileum or in the upper portion of the respiratory tract and then it will be Crohns disease while if the organ enlargement is seen in the rectum or colon then Ulcerative Colitis can be substantiate (Chatu, Subr amanian & Pollok, 2012).Crohns disease as discussed is caused by mycobacteria avium paratuberculosis whereas Ulcerative Colitis is mostly caused by Escherichia coli (Winter et al., 2013). A bacterial finish test using the selective media for the Escherichia coli and Mycobacterium avium paratuberculosis will helper in the illuminance of the exact micro-organism colonizing in the gastrointestinal tract leading to the miniature of the disease.Ananthakrishnan, A. N., Higuchi, L. M., Huang, E. S., Khalili, H., Richter, J. M., Fuchs, C. S., & Chan, A. T. (2012). Aspirin, nonsteroidal anti-inflammatory drug use, and assay for Crohn disease and ulcerative colitisa cohort study. story of internal medicine,156(5), 350-359.Baumgart, D. C., & Sandborn, W. J. (2012). Crohns disease.The Lancet,380(9853), 1590-1605.Bressler, B., Marshall, J. K., Bernstein, C. N., Bitton, A., Jones, J., Leontiadis, G. I., ... & Group, T. U. C. C. (2015). clinical practice guidelines for the medical management of nonhospitalized ulcerative colitis the Toronto consensus.Gastroenterology,148(5), 1035-1058.Chatu, S., Subramanian, V., & Pollok, R. C. G. (2012). Meta? analytic thinking diagnostic medical radiation moving picture in inflammatory bowel disease. alimentary pharmacology & therapeutics,35(5), 529-539.Kyle, J. (2013).Crohns disease. Butterworth-Heinemann.Manninen, P., Karvonen, A. L., Huhtala, H., Rasmussen, M., Salo, M., Mustaniemi, L., ... & Collin, P. (2012). deathrate in ulcerative colitis and Crohns disease. A population-based study in Finland. daybook of Crohns and Colitis,6(5), 524-528.Steenholdt, C., Svenson, M., Bendtzen, K., Thomsen, O. ., Brynskov, J., & Ainsworth, M. A. (2012). penetrative and delayed hypersensitivity reactions to infliximab and adalimumab in a patient with Crohns disease.Journal of Crohns and Colitis,6(1), 108-111.Travera, G. E., Zumarraga, M., Etchechoury, I., Romano, M. I., Cataldi, A., Alvarado Pinedo, M. F., ... & Romero, J. R. (2013). First den omination of Mycobacterium avium paratuberculosis sheep straining in Argentina.Brazilian Journal of Microbiology,44(3), 897-899.Winter, S. E., Winter, M. G., Xavier, M. N., Thiennimitr, P., Poon, V., Keestra, A. M., ... & Popova, I. E. (2013). Host-derived treat boosts growth of E. coli in the inflamed gut.science,339(6120), 708-711.